Lipids and Lipid Derivatives
Medchemexpress LLC D-α-Tocopherol acetate | 58-95-7 | 98.3% | 25 MG
D-α-Tocopherol acetate (D-Vitamin E acetate) is a compound that can be hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine. It acts as an endogenous metabolite and is supplied as a colorless to light yellow liquid. This compound is intended for research use only.
- Can be hydrolyzed to d-alpha-tocopherol and absorbed in the small intestine.
- Inhibits LPS-induced production of NO, prostaglandin E2, and pro-inflammatory cytokines (TNF-α, IFN-γ, IL-1β, and IL-6) in mouse peritoneal macrophages.
- Exhibits a slight suppression on the activation of NF-κB p50 and p65.
Medchemexpress LLC Vitamin K4 | 573-20-6 | 99.9% | 1 G
Vitamin K4 is a chemically synthesized Vitamin K that plays an important role in the normal blood coagulation system. It arrests cells in the S phase of the cell cycle and induces apoptosis, and can be used for research on cancer, including prostate cancer and osteosarcoma.
- Inhibits cell proliferation and induces caspase-dependent apoptosis in PC-3 cells.
- Induces S phase cell cycle arrest in PC-3 and U2OS cells.
- Inhibits the growth of U2OS cells.
- Increases ROS generation and disrupts mitochondrial membrane potential in U2OS cells.
- Inhibits the migration of U2OS cells in vitro.
- Modulates expression of Bcl-2, Bax, PARP, and cleaved-caspase-3.
Sigma Aldrich Fine Chemicals Biosciences (+/-)-alpha-Tocopherol | 10191-41-0 | MFCD00006848 | 100 g
(+/-)-alpha-Tocopherol | Purity: ≥96% | Mol Wt: 430.71 | 10191-41-0 | MFCD00006848 | 100 g
Medchemexpress LLC RVG-Cys acetate | 99.7% | 3369.77 (free acid) | 5 MG
RVG-Cys acetate is a peptide derived from rabies virus glycoprotein (RVG29). It is designed with a Cys attachment to facilitate subsequent conjugation and enhances the specific targeted delivery of proteins in brain tissue and neurons. This product is for research use only.
- Peptide derived from rabies virus glycoprotein (RVG29)
- Cys attached for subsequent conjugation
- Enhances specific targeted delivery of proteins
- Targets brain tissue and neurons
- For research use only
Medchemexpress LLC Vitamin D Receptor Antibody | 10 UL
Vitamin D Receptor Antibody is a rabbit-derived and non-conjugated IgG polyclonal antibody, targeting the Vitamin D Receptor. It is for research use only.
- Immunohistochemistry-Paraffin (IHC-P): 1:100-500 dilution ratio
- Immunohistochemistry-Frozen (IHC-F): 1:100-500 dilution ratio
- Immunocytochemistry/Immunofluorescence (ICC/IF): 1:100-500 dilution ratio
Medchemexpress LLC LSD acetate | 98.0% | 1009.20 | 25 MG
LSD acetate is a peptide that specifically recognizes the lymphatics of C8161 melanoma, but not the lymphatics of normal tissues or tumor blood vessels. When conjugated with a proapoptotic peptide, it can reduce the number of tumor lymphatics. It can be used in the research of targeted therapy and diagnosis of tumor lymphatics.
- Specifically recognizes lymphatics of C8161 melanoma.
- Does not bind to lymphatics of normal tissues or tumor blood vessels.
- Can reduce the number of tumor lymphatics when conjugated with a proapoptotic peptide.
- Useful in research for targeted therapy and diagnosis of tumor lymphatics.
Medchemexpress LLC Elaidic acid-d9 | 1809227-37-9 | 99.0% | 291.52 | 1 MG
Elaidic acid-d9 is deuterium labeled Elaidic acid. Elaidic acid is the major trans fat found in hydrogenated vegetable oils and can be used as a pharmaceutical solvent. It is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Vitamin K1 (Phylloquinone) | 84-80-0 | 450.70 | 1 ML
Vitamin K1 (Phylloquinone) is a naturally occurring vitamin essential for blood coagulation and bone and vascular metabolism. This prenylated naphthoquinone is synthesized by plants, green algae, and some cyanobacteria, acting as a vital electron carrier in photosystem I and an electron acceptor for protein disulfide bond formation. In humans, it functions as vitamin K1, commonly found in green leafy vegetables and vegetable oil.
- Exerts antiproliferative effects and induces apoptosis in colon cancer cell lines.
- Reduces risk of type 2 diabetes in elderly subjects.
- Reverses high-fat diet-induced bone deterioration.
- Promotes wound healing through increased contraction and epithelialization.
Medchemexpress LLC Rkh acetate | 99.8% | 439.51 | 5 MG
RKH acetate exerts protective effects against sepsis-induced death and organ damage. It directly binds to Toll-like receptor 4 (TLR4) and blocks TLR4 signal transduction in immune cells. It is for research use only.
- Target: TLR4
- Appearance: Solid
- Color: White to off-white
- Sequence: Arg-Lys-His
- Solubility in DMSO: 200 mg/mL
- Solubility in H2O: ≥ 30 mg/mL
Medchemexpress LLC GPRP acetate | 157009-81-9 | 98.9% | 485.53 | 25 MG
GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that blocks the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa). This compound enhances free thrombin generation and has demonstrated significant therapeutic potential in animal models, alleviating DSS-induced colitis by improving body weight loss and mortality.
- Inhibits fibrin polymerization.
- Targets platelet membrane glycoprotein IIb/IIIa complex.
- Increases free thrombin generation.
- Alleviates DSS-induced colitis in animal models.
- Reduces DSS-induced shortening of colon length.
- Decreases tissue damage and infiltration of inflammatory cells.
- Lowers levels of inflammatory cytokines in colitis mice.
eMolecules 1219794-57-6 | Tolbutamide-d9 | Toronto Research Chemicals | MFCD06658779 | 279.400 | C12H18N2O3S | 95.000 | [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])NC(=O)NS(=O)(=O)c1ccc(C)cc1 | 2.5mg | 882925946
Tolbutamide-d9 | Toronto Research Chemicals | 1219794-57-6 | MFCD06658779 | 279.400 | C12H18N2O3S | 95.000 | [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])NC(=O)NS(=O)(=O)c1ccc(C)cc1 | 2.5mg | 882925946